This study represents the first phylogenetic reconstruction of lumbrinerid genera using parsimony analyses of 38 morphological characters. Following higher-level phylogenetic analysis, Oenone (Oenonidae) was selected as outgroup. The analysis was restricted to type species for each genus, yielded 24 equally parsimonious trees, which after successive weighting were reduced to one tree (CI= 0.7396). The topology of this tree revealed the separation of the family into four main clades: 1. Lysarete, 2. Arabellonereis, 3. Scoletoma, Lumbrineris, Hilbigneris gen. nov., Kuwaita, Lumbricalus, Sergioneris gen. nov. and Eranno, and 4. Abyssoninoe, Cenogenus, Lumbrinerides, Lumbrineriopsis, Augeneria, Loboneris gen. nov., Gallardoneris gen. nov., Helmutneris gen. nov., and Gesaneris gen. nov.; the position of Ninoe is unclear. A diagnosis of each genus is provided, including the description of six new genera and three new species. A key to lumbrinerid genera is included.