Maldane californiensis is described from deep waters (about 85 m to 650 m) off southern California. It is compared with other species of
Maldane with a dorsal glandular band or ridge posterior to the neuropodial glandular pad of setiger 5. Features of the cephalic and anal plaques, collar, glands, and patterns in the number of uncini per setiger are discussed. The new species is closest in morphology to
M. cuculligera Ehlers, 1887 of the Gulf of Mexico and western Atlantic Ocean (about 200 m to 1,000 m depths) and
M. monilata Fauchald, 1972 from the Middle America and Peru-Chile Trenches (about 1800 m to 3500 m depths). It is hypothesized that these three taxa derived from a common ancestor and that speciation resulted mainly from the uplift of the Panama Isthmus 2 to 3 million years ago.