World Porifera Database

Porifera source details

Name

Tsukamoto, S.; Tane, K.; Ohta, T.; Matsunaga, S.; Fusetani, N.; Van Soest, R. W. M. (2001). Four New Bioactive Pyrrole-Derived Alkaloids from the Marine Sponge Axinella brevistyla. Journal of Natural Products. 64(12): 1576-1578.

SourceID

437834

DOI

10.1021/np010280b [view]

Authors

Tsukamoto, S.; Tane, K.; Ohta, T.; Matsunaga, S.; Fusetani, N.; Van Soest, R. W. M.

Year

2001

Title

Four New Bioactive Pyrrole-Derived Alkaloids from the Marine Sponge Axinella brevistyla

Journal

Journal of Natural Products

Suffix

64(12): 1576-1578

Type

Publication

Link

https://pubs.acs.org/doi/10.1021/np010280b

Full text

Available for editors

[request]

Abstract

Four new alkaloids (1-4) were isolated from the marine sponge Axinella brevistyla, and their structures were determined on the basis of spectroscopic analysis. The alkaloids 1-4 were antifungal against the yeast Saccharomyces cerevisiae at <1.0, <1.0, 30, and 100 µg/disk, respectively. Compounds 1-3 also exhibited cytotoxicity against L1210 cells with IC50 values of 1.1, 0.66, and 2.5 µg/mL, respectively.

Geographical term

Japan

Bibliographical term

Chemistry

Taxonomic term

Porifera

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Sessions

Date

action

2022-09-23 12:11:58Z

created

Cárdenas, Paco

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Homaxinella brevistyla Hoshino, 1981 accepted as Axinella brevistyla (Hoshino, 1981) (source of synonymy)

Central Kuroshio Current for Axinella brevistyla (Hoshino, 1981)

Nontype ZMA 15732, geounit Central Kuroshio Current, identified as Axinella brevistyla (Hoshino, 1981)