Saeki, B.M.; Granato, A.C.; Berlinck, R.G.S.; Magalhães, A.; Schefer, A.B.; Ferreira, A.G.; Pinheiro, U.S.; Hajdu, E. (2002). Two Unprecedented Dibromotyrosine-Derived Alkaloids from the Brazilian Endemic Marine Sponge Aplysina caissara. Journal of Natural Products. 65(5): 796-799.

432046

10.1021/np0105735 [view]

Saeki, B.M.; Granato, A.C.; Berlinck, R.G.S.; Magalhães, A.; Schefer, A.B.; Ferreira, A.G.; Pinheiro, U.S.; Hajdu, E.

2002

65(5): 796-799

Publication

Available for editors   [request]

Two new bromotyrosine-derived alkaloids, caissarine A (1) and caissarine B (2), along with three known biogenetically related alkaloids, aeroplysinin-1, fistularin-3, and the artifact of isolation 2-(3,5-dibromo- 4-dimethoxy-1-hydroxy-2,5-cyclohexadien-1-yl)ethanamide, have been isolated from Aplysina caissara, an endemic species of marine sponge from the Southeastern Brazilian coast. The alkaloids have been identified by analysis of spectroscopic data. While caissarine A has a 2-hydroxyagmatine moiety in its structure, caissarin B is the first naturally occurring compound encompassing the unprecedented 1,7- diamino-3-hydroxyheptane moiety.

South West Atlantic ( =only warm temperate; cold temperate see *SUB)

Chemistry

Porifera

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