Chen C-Y, Shen Y-C, Chen Y-J, Sheu J-H, Duh C-Y. (1999). Bioactive sesquiterpenes from a Taiwanese marine sponge Parahigginsia sp. Journal of Natural Products. 62, 573-576.

482188

Chen C-Y, Shen Y-C, Chen Y-J, Sheu J-H, Duh C-Y

1999

62, 573-576

Publication

https://doi.org/10.1021/np980491p

Available for editors   [request]

Five new sesquiterpenes, parahigginols A-D (1-4) and parahigginic acid (5), have been isolated from a Taiwanese marine sponge Parahigginsia sp. The structural assignments of the new compounds were based on their spectral data, including 1D and 2D NMR. Biological studies revealed that compounds 2-5 exhibited cytotoxicity against murine P-388 and human KB16, A549, and HT-29 tumor cells.

Taiwan

Biochemistry

Porifera

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